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Search Results for " gaba receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T3290 Pikamilone Picamilon,Nicotinoyl-GABA Others
Pikamilone (Picamilon) is an intelligent medicine.
TN1023 Miltirone P450 , GABA Receptor
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
T14571 Bifenazate GABA Receptor
Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.
T4440 Saclofen GABA Receptor
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function...
TQ0119 Cirsimaritin GABA Receptor
Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.
TQ0023 Lorediplon GABA Receptor
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
T5754 Kavain NF-κB , GABA Receptor
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.
T10618 Broflanilide GABA Receptor
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR (IC50: 1.3 nM).
T7794 Zuranolone GABA Receptor
Zuranolone is an agonist of GABAA receptor.
T15775 Lotilaner GABA Receptor , Parasite
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
T4176 Rac-BHFF (R,S)-BHFF GABA Receptor
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo an...
T4728 4-Acetamidobutanoic acid N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID GABA Receptor , Endogenous Metabolite , Antibacterial
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamid...
T3782 Jujuboside A transporter , GABA Receptor
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease.
T7557 Guvacine hydrochloride GABA Receptor
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
T82357 GABA receptor Antagonist 1 GABA Receptor
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P. xylostella, S. frugiperda, S. exigua, and S. litura with respect...
T1065 Baclofen Lioresal GABA Receptor
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...
T8036 6-Methylflavone GABA Receptor
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T16539 Piperazine citrate GABA Receptor
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.
T5375 Loreclezole GABA Receptor
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T26600 Alpidem Ananxyl GABA Receptor
Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar bin...
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